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Galα1-3Gal Oligosaccharides

Xeno and Galili antigens are major antigens responsible for the hyperacute rejection and identified as α-galactosyl epitopes. The first one identified was the Linear-B trisaccharide (Galili et al. 1985, 1987) namely Galα1-3Galβ1-4GlcNAc.

α-Gal epitopes are abundantly expressed on cells of non-primate mammals and new world monkeys whereas humans, apes and old world monkeys lack this epitope but produce against it large amounts of antibodies anti-Gal. This interaction between them is of major clinical significance causing rejection of pig organ transplants in human and monkeys (Zhao Chun chen et al., Glycobiology,vol.11, 2001).

  • Further Reading(s): Caroline Gebus et al. Carbohydrate research, 2012.

Galili & Xeno antigens

Xeno antigen type 1 - 5 mg

trait
GLY074-1

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Galα1-3Galβ1-3GlcNAc
C20H35NO16
FW 545.48
Galili & Xeno antigens

Galili antigen pentaose linked to BSA

Galili antigen pentaose linked to BSA
trait
GLY071-BSA

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Galα1-3Galβ1-4GlcNAcβ1-3Galβ1-4Glc
Galili & Xeno antigens

Xeno Lewisx / α-Gal-Lewisx

Xeno Lewis<sup>x</sup> / α-Gal-Lewis<sup>x</sup>
trait
GLY075

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Galα1-3Galβ1-4(Fucα1-3)GlcNAc
C26H45NO20
FW 691.62
Isoglobo-Series

SSEA-4 hexaose - BSA

trait
GLY131-BSA

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Galα1-3Galβ1-4Glc
C18H32O16
FW 504.43
[56038-36-9]
Isoglobo-Series

IsoGb3-β-O-aminopropyl

trait
GLY070-OAPb

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Galα1-3Galβ1-4Glcβ-O-CH2-CH2-CH2-NH2
Galili & Xeno antigens

Galili antigen undecaose

Galili antigen undecaose
trait
GLY079

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Galα1-3[Galβ1-4GlcNAcβ1-3]4Galβ1-4Glc
C74H124N4O56
FW 1964.76
Isoglobo-Series

Isoforssman antigen pentaose linked to BSA

Isoforssman antigen pentaose linked to BSA
trait
GLY134-BSA

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GalNAcα1-3GalNAcβ1-3Galα1-3Galβ1-4Glc
Galili & Xeno antigens

Galili antigen nonaose

Galili antigen nonaose
trait
GLY078

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Galα1-3[Galβ1-4GlcNAcβ1-3]3Galβ1-4Glc
C60H101N3O46
FW 1600.42
Isoglobo-Series

Isoforssman antigen pentaose

Isoforssman antigen pentaose
trait
GLY134

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GalNAcα1-3GalNAcβ1-3Galα1-3Galβ1-4Glc
C34H58N2O26
FW 910.82
Isoglobo-Series

Isoglobotriaose / iGb3 / 3'-Galactosyl-lactose / Linear B-6 trisaccharide

Isoglobotriaose / iGb3 / 3'-Galactosyl-lactose / Linear B-6 trisaccharide
trait
GLY070

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Galα1-3Galβ1-4Glc
C18H32O16
FW 504.43
[56038-36-9]
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