Galanthus nivalis Lectin (GNA) linked to fluorescein - GNL

Galanthus nivalis Lectin (GNA) linked to fluorescein

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Product code: LEC511-FLUO

Sugar specificity: Mannose (Man)

Sugar specificity: Mannose (Man)

Additional specificity details: α1-3Man ; Methyl-α-mannose (MeαMan)

Structure: Tetrameric lectin composed of four identical subunits of 13 kDa

The lectin is known to agglutinate rabbit erythrocytes but not human erythrocytes. It binds specifically to murine IgM immunoglobulin and human α2 -macroglobulin. It contains little or no carbohydrate and does not need Ca2+ or Mn2+ for binding, since unlike most mannose-specific lectins it is not a metalloprotein. Unlike the majority of mannose-binding lectins, GNA does not bind alpha-linked glucose. GNA has been useful in HIV research. It is also applicable for blood cell agglutination studies but also as a model system to help understand the molecular basis of how proteins recognize carbohydrates.

Synonyms:GNL

Laboratory reagent for research and development only. Not for human or animal use.

specs_LEC511_FLUO.pdf (specs_LEC511_FLUO.pdf) Download (102.08KB)

MSDS_LEC511_FLUO.pdf (MSDS_LEC511_FLUO.pdf) Download (291.21KB)

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