Glycans and Glycoconjugates expertise
BUILD YOUR GLYCAN
The selected monosaccharides, with their respective linkages and side chains when applicable, will automatically fill in the search bar and display matching results from our catalog.
- Monosaccharide :
- Glc
- GlcNAc
- Gal
- GalNAc
- Neu5Ac
- Fuc
- Neu5Gc
- Man
- Fru
- GulA
- ManA
- GalA
- Ara
- GlcA
- For polysaccharide searches, consult our list
-
Linkage :
- α1-2
- α1-3
- α1-4
- α1-5
- α1-6
- α2-3
- α2-6
- α2-8
- β1-2
- β1-3
- β1-4
- β1-6
- β2-1
- Side Chain :
- (
- )
- Functionalization
- Dual-functionalization
- Grafting on proteins
Functionalizations available for this glycan
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Lectins & labeled lectins by Origin (2 products)
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Plant lectins (2 products)
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- mail Customized functionalizations on request
Galanthus nivalis Lectin (GNA) linked to biotin
Product code: LEC511-BT
Sugar specificity: Mannose (Man)
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Sugar specificity: Mannose (Man)
Additional specificity details: α1-3Man ; Methyl-α-mannose (MeαMan)
Structure: Tetrameric lectin composed of four identical subunits of 13 kDa
The lectin is known to agglutinate rabbit erythrocytes but not human erythrocytes. It binds specifically to murine IgM immunoglobulin and human α2 -macroglobulin. It contains little or no carbohydrate and does not need Ca2+ or Mn2+ for binding, since unlike most mannose-specific lectins it is not a metalloprotein. Unlike the majority of mannose-binding lectins, GNA does not bind alpha-linked glucose. GNA has been useful in HIV research. It is also applicable for blood cell agglutination studies but also as a model system to help understand the molecular basis of how proteins recognize carbohydrates.
Synonyms:GNL
Laboratory reagent for research and development only. Not for human or animal use.
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Sugar specificity: Mannose (Man)