Glycans and Glycoconjugates expertise
BUILD YOUR GLYCAN
The selected monosaccharides, with their respective linkages and side chains when applicable, will automatically fill in the search bar and display matching results from our catalog.
- Monosaccharide :
- Glc
- GlcNAc
- Gal
- GalNAc
- Neu5Ac
- Fuc
- Neu5Gc
- Man
- Fru
- GulA
- ManA
- GalA
- Ara
- GlcA
- For polysaccharide searches, consult our list
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Linkage :
- α1-2
- α1-3
- α1-4
- α1-5
- α1-6
- α2-3
- α2-6
- α2-8
- β1-2
- β1-3
- β1-4
- β1-6
- β2-1
- Side Chain :
- (
- )
- Functionalization
- Dual-functionalization
- Grafting on proteins
Functionalizations available for this glycan
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Lectins & labeled lectins by Origin (2 products)
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Bacterial lectins (2 products)
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- mail Customized functionalizations on request
Pseudomonas aeruginosa Lectin A (LecA) linked to biotin
Product code: LEC102-BT
Sugar specificity: Galactose (Gal)
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Sugar specificity: Galactose (Gal)
Additional specificity details: Galili antigen (Galα1-3Galβ1-4GlcNAc) ; Galα1-4Galβ1-4Glc ; Human antigens B ; Pk.2
Structure: Homotetrameric lectin composed of four subunits of 12.8 kDa. One binding site per monomer which requires one calcium cations for binding.
Pseudomonas aeruginosa, is an opportunistic pathogen that produces two small soluble lectins, LecA and LecB, also named respectively PAI-L and PAII-L. LecA had a cytotoxic activity on human epithelial cells in primary culture. The exposure of these cells to concentrations of LecA of >10 μg/mL inhibited their growth and decreased ciliary activity. With higher concentrations of LecA (100 μg/ml), cellular lesions were observed. LecA was also shown to have a cytotoxic effect on the digestive epithelium. LecA agglutinates human and rabbit erythrocytes.
Synonyms:PAI-L ; LEC102-Bt
Laboratory reagent for research and development only. Not for human or animal use.
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Sugar specificity: Galactose (Gal)