Product code: LEC510
Sugar specificity: Mannose (Man)
Additional specificity details: Methyl-α-mannose (MeαMan) ; Manα1-3Man ; Glycoproteins carrying terminally exposed mannose
Structure: Monomeric lectin of 29 kDa
FimH lectin (or type 1 fimbrial lectin) is a lectin-like protein that is incorporated into the tip of surface hair-like structures of E. Coli and other enterobacteria. FimH has a molecular weight of 29 kDa (279 amino acid residues) and is composed of two distinct domains: the C-terminal pilin domain (residues 160-279) that anchors the adhesin to the fimbrial rod and the N-terminal lectin domain (residues 1-156) that is responsible for mannose binding. FimH plays crucial role in bacterial adhesions and diseases.
Synonyms:Type 1 fimbrial lectin
Laboratory reagent for research and development only. Not for human or animal use.