Burkholderia cenocepacia Lectin C - N terminal domain (BC2LC) linked to biotin

Burkholderia cenocepacia Lectin C - N terminal domain (BC2LC) linked to biotin

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Product code: LEC302-BT

Sugar specificity: Fucose (Fuc)

Sugar specificity: Fucose (Fuc)

Additional specificity details: Lewis b ; Lewis Y ; Fucose containing ligands ; H-type 1 trisaccharide (αFuc1-2βGal1-3βGlcNAc) and H-type 3 trisaccharide (αFuc1-2βGal1-3αGalNAc) ; Lewis a

Structure: Trimeric lectin of approximately 41 kDa

Short common fragments such as monosaccharides and disaccharides (e.g. αFuc1-2Gal, αFuc1 3GlcNAc, αFuc1-4GlcNAc) are not efficient ligands and αFuc1-6βGlcNAc, often present on the core disaccharide of animal N-glycans, is not recognized by BC2L-C N term. BC2L-C N-term triggers IL-8 production, and has a potential role in the dysregulation of the proinflammatory response observed in B. cenocepacia lung infections.

Laboratory reagent for research and development only. Not for human or animal use.

specs_LEC302_BT.pdf (specs_LEC302_BT.pdf) Download (106.13KB)

MSDS_LEC302_BT.pdf (MSDS_LEC302_BT.pdf) Download (286.56KB)

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