Product code: LEC302-BT
Sugar specificity: Fucose (Fuc)
Additional specificity details: Lewis b ; Lewis Y ; Fucose containing ligands ; H-type 1 trisaccharide (αFuc1-2βGal1-3βGlcNAc) and H-type 3 trisaccharide (αFuc1-2βGal1-3αGalNAc) ; Lewis a
Structure: Trimeric lectin of approximately 41 kDa
Short common fragments such as monosaccharides and disaccharides (e.g. αFuc1-2Gal, αFuc1 3GlcNAc, αFuc1-4GlcNAc) are not efficient ligands and αFuc1-6βGlcNAc, often present on the core disaccharide of animal N-glycans, is not recognized by BC2L-C N term. BC2L-C N-term triggers IL-8 production, and has a potential role in the dysregulation of the proinflammatory response observed in B. cenocepacia lung infections.
Laboratory reagent for research and development only. Not for human or animal use.