Mannan

Structural description

Mannan that consists of β(1-4)-mannosyl residues is abundant in nature, and is obtained as a pure homopolymer from the endosperm of the monocotyledonous (e.g. Arecaceae family), such as ivory nuts (Phytelephas sp.), dates (Phoenix dactylifera), as well as from the cell walls of several green algae belonging to the Codiaceae and Dasycladaceae families. It is also distributed within some species from Apiaceae, Rubiaceae (Coffea sp.) and Asteraceae.

Mannan is found to be a major constituent of Mycobacteriae and yeast cell wall representing principal surface antigen, with species-specific structure and composition. Saccharomyces cerevisiae mannan differs, for example from that of C. albicans by side chain structure as well as substitution frequency.

Mannan is often compared to another abundant natural polymer, cellulose, because of the similarities in their chemical structures.

Activities and Uses

Mannans are known as important biological response modifiers, which can exhibit a remarkable range of immunopharmacological and therapeutic activities. Aloe species contain O-acetyl-β-D-(1-4) mannan, which have been reported to show antiviral and antiproliferative properties in vivo. Mannan from Aloe saponaria inhibits the proliferative response in normal and tumoral cells (C.L.O. Petkowicz et al., 2007. Carbohydrate Polymers, 69, 659–664).

Recommended paper: R. Hori et al., 2007. Carbohydrate Polymers, 70, 298–303.

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Mannan

Mannan polysaccharide from Yeast

trait
MAN802

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α(1-6) linked mannopyranosyl backbone with α(1-2) and α(1-3) linked D-mannose side chains
Mannan

Mannan polysaccharide (Ivory Nut or Tagua) - 1 g

Mannan polysaccharide (Ivory Nut or Tagua) - 1 g
trait
MAN800

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β(1-4) linked D-mannopyranosyl residues extracted and purified from Ivory Nut (Tagua)
[37251-487-1]
Mannan

Acemannan polysaccharide (Aloe vera)

Acemannan polysaccharide (Aloe vera)
trait
MAN801

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β(1-4) linked D-mannopyranosyl residues
partially O-acetylated extracted and purified from Aloe vera.
Mannan

Mannan oligosaccharides (cut-off<10kDa) - 10 mg

Mannan oligosaccharides (cut-off<10kDa) - 10 mg
trait
MAN810

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β(1-4) linked D-mannose oligosaccharides
prepared by mannan or galactomannan polysaccharide hydrolysis.