Structural description

Scleroglucan is a natural polysaccharide produced by fermentation of the filamentous fungus Sclerotium rolfsii. Its chemical structure consists of a linear β(1-3) D-glucose backbone with one β(1-6) D-glucose side chain every three main residue.

Activities and Uses

Scleroglucan is intended for drug delivery system improvement (Coviello et al., 2005. Molecules, 10(1), 6-33). More precisely, scleroglucan is suitable for the preparation of sustained release tablets and ocular formulations. This peculiar Polysaccharide exhibits antiviral activities against Herpes Virus.

Scleroglucan also has applications in formulation for agriculture. In a view to replace Xanthan gum, Scleroglucan could be especially useful in food manufacturing where a heating process is involved, because of thermal stability that it exhibits (Survase et al.,2007. Fermentative Production of Scleroglucan, Food Technol. Biotechnol. 45 (2) 107–118).


Scleroglucan polysaccharide - One gram

Scleroglucan polysaccharide - One gram

β(1-3) linked D-glucose with side chain of β(1-6) glucose every three unit.