Fucoidan

Structural description

Fucoidans are sulfated fucan polysaccharides occurring in brown marine seaweeds cell wall (Phaeophyceae, mainly Fucales and Laminariales), in sea urchin egg gelatinous coat, and in sea cucumber cuticule.

Numerous variations of the basic structure are found in different species of Phaeophycea. The structure of fucan polysaccharide consists of α(1-3) linked sulphated L-fucose backbone in some order (eg Laminariales) with alternating α(1-3) and α(1-4) linked residues in other orders (e.g. Fucales). Other units (like galactose) and substitutions (acetate) also occur.

Galactofucan is a sulphated (10-30%) backbone dominated by both 3-linked α-fucopyranose and β-galactopyranose moieties. Galactofucan can be extracted from the brown seaweed Undaria pinnatifida and Saccharina longicruris.

Activities and Uses

Fucoidan and galactofucan exhibit numerous potential therapeutic activities. Noteworthy, they have been shown to have anti-inflammatory, anticoagulant/heparin-like activities, antiviral and antiparasitic activities. They can act has antiangiogenic and antitumoral agents.

Recommended papers:

  • Synytsya et al., 2010. Carbohydrate Polymers, vol.81, pp 41-48.
  • Rioux et al., 2010. Phytochem., vol.71.

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Fucoidan

Fucoidan polysaccharide from Fucus v. - 100 mg

Fucoidan polysaccharide from Fucus v.  - 100 mg
trait
FUC100

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Highly sulphated L-fucose polymer from the brown Fucus vesiculosus
[9072-19-9]
Fucoidan

Galactofucan polysaccharide from Undaria p. - 100 mg

Galactofucan polysaccharide from Undaria p. - 100 mg
trait
FUC200

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Sulfated polymer of L-fucose and D-galactose from Undaria pinnatifida.
[9061-39-6]
Fucoidan

Fucoidan polysaccharide from Chorda filum - 100 mg

Fucoidan polysaccharide from Chorda filum - 100 mg
trait
FUC300

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Highly sulphated L-fucose polymer from Chorda filum [9072-19-9]
Fucoidan

Fucoidan oligosaccharides (Cut-off<10kDa) from Chorda filum - 10 mg

trait
FUC310

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Highly sulphated L-fucose oligomer from Chorda filum polysaccharide hydrolysis.
Fucoidan

Fucoidan polysaccharide from Ascophyllum n. - 100mg

Fucoidan polysaccharide from Ascophyllum n. - 100mg
trait
FUC400

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Highly sulphated L-fucose polymer from Ascophyllum nodosum.
[9072-19-9]
Fucoidan

Fucoidan polysaccharide from Durvillea a. - 100mg

Fucoidan polysaccharide from Durvillea a. - 100mg
trait
FUC500

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Highly sulphated L-fucose polymer from Durvillea antarctica.
[9072-19-9]
Fucoidan

Fucoidan polysaccharide Kit (4 x 100 mg)

Fucoidan polysaccharide Kit (4 x 100 mg)
trait
FUC600

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Individually packaged Highly sulphated L-fucose polymer extracted and purified from 4 species of brown seaweed.