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Glycan Oligosaccharides

  • Elicityl’s OligoTech® encompasses a collection of almost 200 glycan-type bioactive oligosaccharides involved in key biological pathways (cell adhesion, immunological recognition, embryogenesis, oncogenesis, infection…).

 

  • The collection comprises a large diversity of bioactive oligosaccharides such as carbohydrate determinants of human blood groups (ABH, Lewis, P) and carbohydrate portions of the major glycosphingolipids (gangliosides, globosides).

 

  • These oligosaccharides have numerous potential applications in different fields as anti-cancer vaccines, anti-infective, anti-neurodegenerative, diagnosis or functional food.

 

  • Elicityl also provides Glycobricks®, functionalized oligosaccharides which could be used as elementary building blocks for click chemistry.

 

  • The products are available from the mg to the multi-gram scale.
Ganglio-Series

aGM2 Ganglioside sugar-N-Acetyl-propargyl

aGM2  Ganglioside sugar-N-Acetyl-propargyl
trait
GLY104-NPR

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GalNAcβ1-4Galβ1-4Glc-NAc-propargyl
Ganglio-Series

aGM2 / Ganglioside sugar / asialo GM2 / GA2

aGM2 / Ganglioside sugar / asialo GM2 / GA2
trait
GLY104

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GalNAcβ1-4Galβ1-4Glc
C20H35NO16
FW 545.48
Ganglio-Series

Fucosyl GM1 Ganglioside sugar

Fucosyl GM1 Ganglioside sugar
trait
GLY103

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Fucα1-2Galβ1-3GalNAcβ1-4(Neu5Acα2-3)Galβ1-4Glc
C43H71N2O33Na
FW 1168.00
Lewis Antigens

Lewis X tetraose-N-acetyl-propargyl

Lewis X tetraose-N-acetyl-propargyl
trait
GLY050-NPR

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Galβ1-4(Fucα1-3)GlcNAcβ1-3Galβ-NAc-propargyl
Ganglio-Series

aGM1 / Ganglioside sugar asialo GM1 / GA1

aGM1 / Ganglioside sugar  asialo GM1  / GA1
trait
GLY102

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Galβ1-3GalNAcβ1-4Galβ1-4Glc
C26H45NO21
FW 707.62
[75645-24-8]
Lewis Antigens

Lewis X tetraose-Nacetyl-spacer1-NH2

Lewis X tetraose-Nacetyl-spacer1-NH2
trait
GLY050-Nac-sp1-NH2

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Galβ1-4(Fucα1-3)GlcNAcβ1-3Galβ-NAc-sp1-NH2
Ganglio-Series

GT1c Ganglioside sugar

GT1c Ganglioside sugar
trait
GLY101

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Galβ1-3GalNAcβ1-4(Neu5Acα2-8Neu5Acα2-8
Neu5Acα2-3)Galβ1-4Glc
C59H93N4O45Na3
FW 1647.33
Lewis Antigens

LewisX (LeX) hexaose linked to BSA / Lacto-N-neoDiFucohexaose-BSA / LNnDFH-BSA

LewisX (LeX) hexaose linked to BSA / Lacto-N-neoDiFucohexaose-BSA / LNnDFH-BSA
trait
GLY051-BSA

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Galβ1-4(Fucα1-3)GlcNAcβ1-3Galβ1-4(Fucα1-3)Glc
Lewis Antigens

Lewisb (Leb) tetraose

Lewis<sup>b</sup> (Le<sup>b</sup>) tetraose
trait
GLY045

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Fucα1-2Galβ1-3(Fucα1-4)GlcNAc
C26H45NO19
FW 675.63
[80081-06-7]
Ganglio-Series

GT1a Ganglioside sugar

GT1a Ganglioside sugar
trait
GLY100

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Neu5Acα2-8Neu5Acα2-3Galβ1-3GalNAcβ1-4
(Neu5Acα2-3)Galβ1-4Glc
C59H93N4O45Na3
FW 1647.33
Ganglio-Series

GD1b Ganglioside sugar

GD1b Ganglioside sugar
trait
GLY099

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Galβ1-3GalNAcβ1-4(Neu5Acα2-8Neu5Acα2-3)
Galβ1-4Glc
C48H77N3O37Na2
FW 1334.09
Lewis Antigens

Blood group B LewisY antigen pentaose type 2

Blood group B Lewis<sup>Y</sup> antigen pentaose type 2
trait
GLY038-5

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Galα1-3(Fucα1-2)Galβ1-4(Fucα1-3)GlcNAc
C32H55NO24
FW 837.77
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